Effects of Advanced Glycation End Products

on Thyroid Cancer

Department of Surgery, the Medical University of South Carolina (MUSC)

Several experimental results in the Turner and Findlay labs have pointed to advanced glycation end products (AGEs) also affecting the thyroid. To explore this topic further, Mahsa Javid, M.D., Ph.D., has built a team of clinician-scientists and garnered funding.

 

As a member of the Turner lab, I have trained and consulted Dr. Javid and her team to give them the tools and perspective needed to perform successful research. This training has included:

 

  • Foundational lab practices

    • Record-keeping

    • Aseptic technique

    • Safety

  • Experimental design

    • Positive and negative controls

    • Technical and biological replicates

  • Experimental techniques

    • Tissue culture

    • Western Blot

    • Migration assay

    • Proliferation assay

  • Statistical analysis

    • GraphPad​

  • Equipment operation

    • Standard lab equipment

    • Epoch plate reader​

    • c300 Azure imager

 

Providing my experience and perspective to this unique team of researchers has been one of the highlights of my time at the Medical University of South Carolina (MUSC). As a result of my help, they have established differential protein expression and cell migration of immortalized thyroid cells in response to AGE treatment, and have begun to elucidate the possible effects of AGEs on thyroid cell proliferation and apoptosis.

 

This research is currently ongoing and unpublished, therefore no data is displayed.